CDS
| Accession Number | TCMCG027C32263 |
| gbkey | CDS |
| Protein Id | XP_018843895.1 |
| Location | complement(join(193345..193515,194985..195039,195137..195183,195303..195359,195457..195571,201869..201950,202260..202344,202417..202536,202748..202798,202901..202966,203173..203220,203327..203375,203467..203520,203650..203709,203879..203937,204071..204187,204281..204292)) |
| Gene | LOC109008307 |
| GeneID | 109008307 |
| Organism | Juglans regia |
Protein
| Length | 415aa |
| Molecule type | protein |
| Topology | linear |
| Data_file_division | PLN |
| dblink | BioProject:PRJNA350852 |
| db_source | XM_018988350.2 |
| Definition | flap endonuclease 1 isoform X1 [Juglans regia] |
EGGNOG-MAPPER Annotation
| COG_category | L |
| Description | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA |
| KEGG_TC | - |
| KEGG_Module | - |
| KEGG_Reaction | - |
| KEGG_rclass | - |
| BRITE |
ko00000
[VIEW IN KEGG] ko00001 [VIEW IN KEGG] ko01000 [VIEW IN KEGG] ko03032 [VIEW IN KEGG] ko03400 [VIEW IN KEGG] ko04147 [VIEW IN KEGG] |
| KEGG_ko |
ko:K04799
[VIEW IN KEGG] |
| EC | - |
| KEGG_Pathway |
ko03030
[VIEW IN KEGG] ko03410 [VIEW IN KEGG] ko03450 [VIEW IN KEGG] map03030 [VIEW IN KEGG] map03410 [VIEW IN KEGG] map03450 [VIEW IN KEGG] |
| GOs | - |
Sequence
| CDS: ATGGGTATAAAGGGTTTAACGAAGCTCTTGGCGGACAATGCCCCAAAGGCCATGAAGGAGCAGAAATTCGAGAGCTATTTTGGCCGCAAAGTCGCTATCGACGCCAGCATGAGCATTTATCAGTTCCTCATTGTTGTGGGAAGAATTGGGACTGAGATGCTGACCAATGAGGCTGGTGAAGTTACTAGTCATCTGCAAGGCATGTTTACGCGGACAATAAGACTTCTGGAAGCTGGAATAAAGCCGGTCTATGTTTTTGATGGGAAGCCTCCAGATCTGAAAAAACAAGAGCTGGCAAAACGTTACTCGAAGAGGGCCGATGCTAGCCAGGATTTGGCAGAAGCCGTGGAGACTGGGAATAAGGAAGATATTGAGAAATTCAGTAAACGTACAGTGAAGGTGACAAAGCAGCACAATGAGGACTGCAAAAGACTGTTAAGACTCATGGGAGTGCCTGTAATTGAGGCTCCTTCAGAAGCAGAGGCACAATGTGCTGCACTTTGCAAATCAGGAAAGGTTTATGCTGTGGCTTCAGAAGACATGGACTCCCTAACATTTGGAGCTCCCCGGTTCCTTCGCCATTTGATGGATCCTAGCTCAAGAAAAGTCCCAGTAATGGAATTTGAAGTTGCAAAGACCTTGGAGGAACTAAATCTTACTATGGATCAATTCATTGATTTATGCATTCTTTCTGGATGTGATTACTGTGACAGCATTCGAGGAATTGGAGGGCAGACTGCTTTGAAGCTCATCCGTCAACATGGCTCTATTGAGAACATATTGGAGAACATAAACAAAGAGAGGTTCCATATACCAGATGATTGGCCATACCAAGAGGCTCGGCAGCTTTTTAAAGAACCAGTAGTCTATACTGATGAAGAGCAACTTGAGATTAAGTGGACTGCTCCAGATGAAGAAGGACTGATTACCTTTCTTGTGAATGAAAATGGATTCAACAGTGACAGAGTGACAAAGGCAATAGAAAAAATTAAAGCAGCCAAGAACAAGTCAGCTCAGGGCCGATTAGAGTCATTTTTTAAGCCAGTTGCTAACCCACCTGCACCTATTAAACGAAAGGAAAGCAAATGCGTGCTTAGATCTCCCAGACCAGCAATTGGGCATAAGATGTTTTCTCTTCATGCATCTAGGTCCAGGCTCATGGTCCATGCCAGCTTGAGCTTGCCAATCCCGGACCTAGGTGTCAAGAACTCCACGTCATTATCCACAGGTGTCATCTTCAGAGCATGA |
| Protein: MGIKGLTKLLADNAPKAMKEQKFESYFGRKVAIDASMSIYQFLIVVGRIGTEMLTNEAGEVTSHLQGMFTRTIRLLEAGIKPVYVFDGKPPDLKKQELAKRYSKRADASQDLAEAVETGNKEDIEKFSKRTVKVTKQHNEDCKRLLRLMGVPVIEAPSEAEAQCAALCKSGKVYAVASEDMDSLTFGAPRFLRHLMDPSSRKVPVMEFEVAKTLEELNLTMDQFIDLCILSGCDYCDSIRGIGGQTALKLIRQHGSIENILENINKERFHIPDDWPYQEARQLFKEPVVYTDEEQLEIKWTAPDEEGLITFLVNENGFNSDRVTKAIEKIKAAKNKSAQGRLESFFKPVANPPAPIKRKESKCVLRSPRPAIGHKMFSLHASRSRLMVHASLSLPIPDLGVKNSTSLSTGVIFRA |